clavulanic acids การใช้

• Rarely, liver toxicity ) has been associated with amoxicillin / clavulanic acid.
• Proclavaminate amidinohydrolase is involved in clavulanic acid biosynthesis.
• This enzyme participates in clavulanic acid biosynthesis.
• Augmentin 250, for example, contains 250 mg of amoxicillin and 125 mg of clavulanic acid.
• Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic.
• Thus imipenem / cilastatin, like amoxicillin / clavulanic acid, is a commonly used combination product.
• Only Amoxicilline-Clavulanic acid ( AMC ) and Chloramphenicol ( C ) show an inhibition of bacterial growth.
• Use of the amoxicillin / clavulanic acid combination for more than one week has caused mild hepatitis in some patients.
• Bacteria often develop resistance to ?-lactam antibiotics by synthesizing a ?-lactamase inhibitors such as clavulanic acid.
• Adjunctive antibiotics in the form of amoxicillin plus clavulanic acid does not increase the clinical pregnancy rate compared with no antibiotics.
• The first choice is amoxicillin with clavulanic acid, and if the person is penicillin-allergic, doxycycline and metronidazole.
• Clavulanic acid is a suicide inhibitor, covalently bonding to a serine residue in the active site of the ?-lactamase.
• Ticarcillin is also often paired with a & beta;-lactamase inhibitor such as clavulanic acid ( co-ticarclav ).
• Clavulanic acid has negligible intrinsic antimicrobial activity, despite sharing the ?-lactam ring that is characteristic of ?-lactam antibiotics.
• Because of concern about necrotizing enterocolitis, amoxicillin or erythromycin has been recommended, but not amoxicillin + clavulanic acid ( co-amoxiclav ).
• Ticarcillin ( often used in combination with clavulanic acid under the designation timentin ), amikacin sulfate, penicillin, and gentamicin are commonly used.
• Combo pills like Ezetimibe / simvastatin ( Vytorin ) and amoxicillin / clavulanic acid ( Augmentin ) are sold because both drugs treat the same condition.
• Clavulanic acid ( " Streptomyces clavuligerus " ) is used in combination with some antibiotics ( like amoxicillin ) to weaken bacterial-resistance.
• Clavulanic acid acts as an inhibitor of a wide range of beta-lactamase enzymes that are used by various microorganisms to resist beta-lactam antibiotics.
• Treatment with ampicillin / sulbactam, amoxicillin / clavulanic acid, or clindamycin is appropriate if deep oropharyngeal abscesses are present, in conjunction with aspiration or drainage.